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Foslinanib
CAS No. 1256037-60-1
Foslinanib( TRX-818 | TRX818 )
Catalog No. M11045 CAS No. 1256037-60-1
Foslinanib (TRX-818) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
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| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameFoslinanib
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NoteResearch use only, not for human use.
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Brief DescriptionFoslinanib (TRX-818) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities.
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DescriptionFoslinanib (TRX-818) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities, induces cancer cell apoptosis and inhibits cancer cell proliferation; also prevents tumor cell VM by blocking the formation of vasculogenic-like tubular structures through an as of yet undetermined mechanism of action.Liver Cancer Phase 2 Clinical
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In Vitro——
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In Vivo——
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SynonymsTRX-818 | TRX818
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaCancer
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IndicationLiver Cancer
Chemical Information
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CAS Number1256037-60-1
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Formula Weight365.253
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Molecular FormulaC16H13FNO6P
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Purity>98% (HPLC)
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Solubility——
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SMILESO=P(O)(OC1=C(OC)C=CC(NC(C2=CC=CC(F)=C2)=C3)=C1C3=O)O
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Chemical Name2-(3-fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin5-yl dihydrogen phosphate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Trans-Anethole
Anethole (anise camphor) is an organic compound that is widely used as a flavoring substance.
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SBI993
SBI993 is an analog of SBI-477 and can be used as a biomarker to confirm the expected action of MondoA target gene expression in vivo. SBI993 reduces muscle TAG levels and hepatic steatosis.
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Cathepsin S substrat...
Ac-KQKLR-AMC (Cathepsin S substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.This peptide is a cathepsin S substrate fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). It can be used to measure cathepsin S activity.)
