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Folinic acid
CAS No. 58-05-9
Folinic acid( —— )
Catalog No. M33999 CAS No. 58-05-9
Folinic acid (Leucovorin) is a biofolate used in the treatment of methotrexate (MTX) toxicity reduction and as an adjuvant therapy for colon cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 31 | In Stock |
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| 25MG | 46 | In Stock |
|
| 50MG | 64 | In Stock |
|
| 100MG | 90 | In Stock |
|
| 500MG | 215 | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameFolinic acid
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NoteResearch use only, not for human use.
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Brief DescriptionFolinic acid (Leucovorin) is a biofolate used in the treatment of methotrexate (MTX) toxicity reduction and as an adjuvant therapy for colon cancer.
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DescriptionFolinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity.
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In Vitro——
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In VivoAnimal Model:24 Balb/c young growing male mice aged 3 weeks (11.88 ± 0.25 g)Dosage:7.0 mg/kg Administration:Intraperitoneal injection; every second day; for 3 weeks Result:Following MTX administration appears to reverse this growth inhibition.
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorEndogenous Metabolite | Antifolate
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Research Area——
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Indication——
Chemical Information
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CAS Number58-05-9
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Formula Weight473.44
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Molecular FormulaC20H23N7O7
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (528.05 mM; Ultrasonic )
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SMILESNc1nc2NCC(CNc3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)N(C=O)c2c(=O)[nH]1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Dodecanoylcarnitine
Dodecanoylcarnitine ((-)-Lauroylcarnitine) has been associated with disturbances in fatty acid oxidation, and the use of Dodecanoylcarnitine resulted in an increase in the permeability of salmon calcitonin.
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5'-DEOXYADENOSINE
5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material which has long been of interest in understanding the mechanism of aging neurodegenerative diseases and carcinogenesis.
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Heparan Sulfate
Heparan Sulfate is a complex and linear polysaccharide, exists as part of glycoproteins named heparan sulfate proteoglycans, which are expressed abundantly on the cell surface and in the extracellular matrix.
