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Home - Products - Antibody Drug Conjugates (ADC) - ADCs Linker/Click Chemistry - Fmoc-NH-PEG8-CH2CH2COOH

Fmoc-NH-PEG8-CH2CH2COOH

CAS No. 756526-02-0

Fmoc-NH-PEG8-CH2CH2COOH( —— )

Catalog No. M33361 CAS No. 756526-02-0

Fmoc-NH-PEG8-CH2CH2COOH is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) for forming antibody-drug conjugates .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Fmoc-NH-PEG8-CH2CH2COOH
  • Note
    Research use only, not for human use.
  • Brief Description
    Fmoc-NH-PEG8-CH2CH2COOH is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) for forming antibody-drug conjugates .
  • Description
    Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • In Vitro
    ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    ADC Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    756526-02-0
  • Formula Weight
    663.75
  • Molecular Formula
    C34H49NO12
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(OC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fulcher JM, et al. Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag. Org Biomol Chem. 2019 Dec 28;17(48):10237-10244.?
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