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FLT3-IN-10

CAS No. 2088735-51-5

FLT3-IN-10( 2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-5-(4-fluorophenyl)-N-phenyl-1,3-oxazol-2-amine )

Catalog No. M28938 CAS No. 2088735-51-5

FLT3-IN-10 (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for the treatment of FLT3-mutated acute myeloid leukemia (AML).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    FLT3-IN-10
  • Note
    Research use only, not for human use.
  • Brief Description
    FLT3-IN-10 (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for the treatment of FLT3-mutated acute myeloid leukemia (AML).
  • Description
    FLT3-IN-10 (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for the treatment of FLT3-mutated acute myeloid leukemia (AML).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-5-(4-fluorophenyl)-N-phenyl-1,3-oxazol-2-amine
  • Pathway
    Angiogenesis
  • Target
    FLT
  • Recptor
    neuropeptide Y (NPY) Y1 receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2088735-51-5
  • Formula Weight
    254.26
  • Molecular Formula
    C15H11FN2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (491.62 mM)
  • SMILES
    FC=1C=CC(=CC1)C=2OC(=NC2)NC=3C=CC=CC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Antal-Zimanyi I, et al. Pharmacological characterization and appetite suppressive properties of BMS-193885, a novel and selective neuropeptide Y(1) receptor antagonist. Eur J Pharmacol. 2008 Aug 20;590(1-3):224-32.
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