FEN1-IN-2( —— )

Catalog No. M35240 CAS No. 824983-94-0

FEN1-IN-2 is a selective and potent inhibitor of flap endonuclease 1 (FEN1), inhibits FEN1 and XPG, has potential anticancer activity, and can be used to study DNA damage repair.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

FEN1-IN-2
Note

Research use only, not for human use.
Brief Description

FEN1-IN-2 is a selective and potent inhibitor of flap endonuclease 1 (FEN1), inhibits FEN1 and XPG, has potential anticancer activity, and can be used to study DNA damage repair.
Description

FEN1-IN-2 (compound 20) is a flap endonuclease 1 (FEN1) inhibitor, with IC50 values of 3 nM and 226 nM for FEN1 and XPG, respectively.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

824983-94-0
Formula Weight

393.42
Molecular Formula

C20H15N3O4S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (254.18 mM; Ultrasonic )
SMILES

O=C(N)C1=CC=C(C=C1)C=2C=CC=C(C2)CN3C(=O)N(O)C(=O)C=4SC=CC43
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. L Nathan Tumey, et al. The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors. Bioorg Med Chem Lett. 2005 Jan 17;15(2):277-81.?

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