Cart
sales@molnova.com
FC-116
CAS No. 2417298-29-2
FC-116( —— )
Catalog No. M36931 CAS No. 2417298-29-2
FC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 128 | In Stock |
|
| 5MG | 188 | In Stock |
|
| 10MG | 312 | In Stock |
|
| 25MG | 533 | In Stock |
|
| 50MG | 760 | In Stock |
|
| 100MG | 981 | In Stock |
|
| 500MG | 2007 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameFC-116
-
NoteResearch use only, not for human use.
-
Brief DescriptionFC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice.
-
DescriptionFC-11 is a Tubulin inhibitor that effectively inhibits tumor growth in mice. FC-11 can also induce endoplasmic reticulum (ER) stress to generate excess reactive oxygen species (ROS), leading to mitochondrial damage, thereby promoting apoptosis in colorectal cancer (CRC) cells by targeting microtubules. FC-11 can be used in cancer research.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis | Microtubule Associated
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2417298-29-2
-
Formula Weight369.39
-
Molecular FormulaC21H20FNO4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC(=C(/C(=O)C1=CC(OC)=C(OC)C(OC)=C1)\C)\C=2C=3C(NC2)=CC(F)=CC3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Liu X, et al. Fluoroindole chalcone analogues targeting the colchicine binding site of tubulin for colorectal oncotherapy. Eur J Med Chem. 2023 Sep 5;257:115540.?
molnova catalog
related products
-
Pyrazoloacridine
Pyrazoloacridine is a nucleic acid binding agent that inhibits the activity of topo I and II with an IC50 of 1.25 μM in K562 cells. Pyrazoloacridine shows anti-cancer activity.
-
AOH1996
AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC).
-
RSH-7
RSH-7 is a potent dual inhibitor of BTK and FLT3, with IC50s of 47 and 12 nM, respectively.RSH-7 has antiproliferative and antitumor activities, inducing apoptosis and inhibiting BTK and FLT3 signaling.
