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F1324

CAS No. ——

F1324( —— )

Catalog No. M30261 CAS No. ——

F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. F1324 exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    F1324
  • Note
    Research use only, not for human use.
  • Brief Description
    F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. F1324 exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI.
  • Description
    F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. F1324 exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI.(In Vitro):F1324 binds to BCL6(5-129) with KD and IC50 values of 0.57 nM and 1 nM according to the results of an SPR analysis and cell-free ELISA assay, respectively. F1324 binds BCL6 not only in cell-free but also cellbased conditions.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    IC50: 1 nM (BCL6)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    1765.04
  • Molecular Formula
    C83H121N21O20S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    Sequence:Ac-{Leu}{Trp}{Tyr}{Thr}{Asp}{Ile}{Arg}{Met}{Ser}{Trp}{Arg}{Val}{Pro}-OH

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Sakamoto K, et al. Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship. Biochem Biophys Res Commun. 2017 Jan 8;482(2):310-316.
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