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F1063-0967
CAS No. 613225-56-2
F1063-0967( F1063-0967 )
Catalog No. M18899 CAS No. 613225-56-2
F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 27 | In Stock |
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| 5MG | 41 | In Stock |
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| 10MG | 67 | In Stock |
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| 50MG | 177 | In Stock |
|
| 100MG | 259 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameF1063-0967
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NoteResearch use only, not for human use.
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Brief DescriptionF1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM.
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DescriptionF1063-0967 is a novel inhibitor of dual-specificity phosphatase 26 (DUSP26), inducing apoptosis in IMR-32 cell line.
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In VitroF1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM. At concentration above 0.1 μM, F1063-0967 remarkably induces IMR32 cell apoptosis. F1063-0967 induces apoptosis in IMR-32 cell line with an IC50 value of 4.13 μM. F1063-0967 has no effect on HL7702 cell line, and little inhibition effect on SH-SY5Y cell line.
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In Vivo——
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SynonymsF1063-0967
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorDUSP26
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Research Area——
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Indication——
Chemical Information
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CAS Number613225-56-2
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Formula Weight484.59
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Molecular FormulaC24H24N2O5S2
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Purity>98% (HPLC)
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SolubilityDMSO : 125 mg/mL 257.95 mM
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SMILESS=C3S\C(=C/c1ccc(C)cc1)C(=O)N3CCCCCC(=O)Nc2ccc(C(=O)O)c(O)c2
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Chemical Name(Z)-2-Hydroxy-4-{6-[5-(4-methyl-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-hexanoylamino}-benzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ren JX, et al. Identification of novel dual-specificity phosphatase 26 inhibitors by a hybrid virtual screening approach based on pharmacophore and molecular docking. Biomed Pharmacother. 2017 May;89:376-385.
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