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Epirizole

CAS No. 18694-40-1

Epirizole( DA-398 | DA398 | DA 398 | Methopyrimazole | Dalex | Mebron | Mepirizole )

Catalog No. M27114 CAS No. 18694-40-1

Epirizole is a pyrimidinyl pyrazole with antipyretic, analgesic, and anti-inflammatory activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Epirizole
  • Note
    Research use only, not for human use.
  • Brief Description
    Epirizole is a pyrimidinyl pyrazole with antipyretic, analgesic, and anti-inflammatory activity.
  • Description
    Epirizole is a pyrimidinyl pyrazole with antipyretic, analgesic, and anti-inflammatory activity.(In Vitro):In Caco-2 cells, Epirizole (1, 10, 100, and 1000 μM) increases the level of MDR1 mRNA expression.
  • In Vitro
    Epirizole (1-1000 μM; 24 h) increases MDR1 mRNA expression in Caco-2 cells. RT-PCRCell Line:Caco-2 cells Concentration:1, 10, 100, and 1000 μM Incubation Time:24 hours Result:Increased the level of MDR1 mRNA expression.
  • In Vivo
    ——
  • Synonyms
    DA-398 | DA398 | DA 398 | Methopyrimazole | Dalex | Mebron | Mepirizole
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    18694-40-1
  • Formula Weight
    234.259
  • Molecular Formula
    C11H14N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (1067.19 mM)
  • SMILES
    COc1cc(C)nn1-c1nc(C)cc(OC)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Proskuriakova TV, Gurtovenko VM, Gorshkova EP. [Comparative evaluation of the effect of carbidine and levamisole on the E-rosette-forming activity of the lymphocytes in alcoholic intoxication]. Farmakol Toksikol. 1989 Jan-Feb;52(1):94-8. Russian.
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