Cart
sales@molnova.com
Elevenostat
CAS No. 1454902-97-6
Elevenostat( JB3-22 )
Catalog No. M28876 CAS No. 1454902-97-6
Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235?μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 35 | In Stock |
|
| 10MG | 58 | In Stock |
|
| 25MG | 110 | In Stock |
|
| 50MG | 177 | In Stock |
|
| 100MG | 330 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameElevenostat
-
NoteResearch use only, not for human use.
-
Brief DescriptionElevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235?μM.
-
DescriptionElevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235?μM.(In Vitro):Elevenostat induced cell death in MM cell lines.(In Vivo):Elevenostat produced similar anti-MM activity in vivo, improving survival among mice inoculated with 5TGM1 MM cells.
-
In Vitro——
-
In Vivo——
-
SynonymsJB3-22
-
PathwayCell Cycle/DNA Damage
-
TargetHDAC
-
RecptorTelomerase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1454902-97-6
-
Formula Weight315.32
-
Molecular FormulaC16H17N3O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (792.85 mM)
-
SMILESCOc(cccc1)c1NC(NCc(cc1)ccc1C(NO)=O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Fleming AM, et al. Human DNA Repair Genes Possess Potential G-Quadruplex Sequences in Their Promoters and 5'-Untranslated Regions. Biochemistry. 2018 Feb 13;57(6):991-1002.
molnova catalog
related products
-
Marbostat-100
Marbostat-100 is a potent, selective HDAC6 inhibitor with Ki of 0.7 nM.
-
EDO-S101
EDO-S101 (Tinostamustine)?is a fusion molecule comprising of the alkylator bendamustine and the HDAC-inhibitor vorinostat.
-
TMP-195
A first-in-class, potent, selective class IIa HDACs (HDAC4, HDAC5, HDAC7 and HDAC9) inhibtior with IC50 of 60, 59, 26, and 15 nM, respectively.
