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Dyngo-4a

CAS No. 1256493-34-1

Dyngo-4a( Dyngo-49 | Dyngo 49 | Hydroxy Dynasore )

Catalog No. M17909 CAS No. 1256493-34-1

Dyngo-4a , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dyngo-4a
  • Note
    Research use only, not for human use.
  • Brief Description
    Dyngo-4a , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respectively.
  • Description
    Dyngo-49 is a dynamin inhibitor.
  • In Vitro
    ——
  • In Vivo
    Animal Model:CD-1 mice.Dosage:30 mg/kg Administration:Intraperitoneal injection; 1.5–2 h before BoNT/A injection Result:Protected BoNT/A-induced paralysis in vivo.
  • Synonyms
    Dyngo-49 | Dyngo 49 | Hydroxy Dynasore
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DynI (brain)| DynI (rec)| DynII (rec)
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    1256493-34-1
  • Formula Weight
    338.31
  • Molecular Formula
    C18H14N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (147.79 mM)
  • SMILES
    c1c(c(cc2ccccc12)O)C(=O)NN=Cc1c(cc(c(c1)O)O)O
  • Chemical Name
    3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5-trihydroxyphenyl)methylene]hydrazide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Harper CB., Targeting membrane trafficking in infection prophylaxis: dynamin inhibitors. Trends Cell Biol. 2013 Feb;23(2):90-101.
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