Home - Products - Angiogenesis - EGFR - Dihydroberberine

Dihydroberberine

CAS No. 483-15-8

Dihydroberberine( —— )

Catalog No. M21509 CAS No. 483-15-8

Dihydroberberine has anti-atherosclerotic anti-inflammatory hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interaction with hERG.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	87	In Stock
10MG	155	In Stock
25MG	290	In Stock
50MG	430	In Stock
100MG	619	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Dihydroberberine
Note

Research use only, not for human use.
Brief Description

Dihydroberberine has anti-atherosclerotic anti-inflammatory hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interaction with hERG.
Description

Dihydroberberine has anti-atherosclerotic anti-inflammatory hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interaction with hERG.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

EGFR
Recptor

hERG| HSP90
Research Area

——
Indication

——

Chemical Information

CAS Number

483-15-8
Formula Weight

337.4
Molecular Formula

C20H19NO4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 20 mg/mL (59.28 mM)
SMILES

COc(ccc1c2CN(CCc(c3c4)cc5c4OCO5)C3=C1)c2OC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Yu D et al. Inhibitory effects and mechanism of dihydroberberine on hERG channels expressed in HEK293 cells. PLoS One. 2017 Aug 1;12(8):e0181823.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Epertinib hydrochlor...

Epertinib hydrochloride shows potent antitumor activity.?
Avitinib

Avitinib (AC-0010, AC0010) is an orally available, irreversible, and mutant-selective EGFR inhibitor with IC50 of 0.18 nM against EGFR L858R/T790M.
A-935142

A-935142 is a human ether-a-go-go-related gene (hERG, Kv 11.1) channel activator that enhances hERG currents by slowing inactivation, promoting activation, reducing inactivation, and shortening atrial and ventricular repolarization in a complex manner.

Sign In Join Free