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DNDI-6148

CAS No. 2243909-59-1

DNDI-6148( —— )

Catalog No. M35150 CAS No. 2243909-59-1

DNDI-6148 has anti-experimental cutaneous leishmaniasis activity and can be used to study visceral leishmaniasis by inhibiting Leishmania protozoa cleavage and polyadenylation-specific factor (CPSF3) endonuclease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    DNDI-6148
  • Note
    Research use only, not for human use.
  • Brief Description
    DNDI-6148 has anti-experimental cutaneous leishmaniasis activity and can be used to study visceral leishmaniasis by inhibiting Leishmania protozoa cleavage and polyadenylation-specific factor (CPSF3) endonuclease.
  • Description
    DNDI-6148 is a novel preclinical candidate for the research of visceral leishmaniasis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Parasite
  • Recptor
    Parasite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2243909-59-1
  • Formula Weight
    335.13
  • Molecular Formula
    C16H14BN5O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NC1=CC=C2C(=C1)B(O)OC2)C=3N=NN(C4=NC=CC=C4)C3C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mowbray CE, et al. DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis. J Med Chem. 2021 Nov 11;64(21):16159-16176. ?
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