DBIBB( —— )

Catalog No. M33784 CAS No. 1569309-92-7

DBIBB is a non-lipid agonist of specific lysophosphatidic acid (LPA2) type 2 G-protein-coupled receptor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

DBIBB
Note

Research use only, not for human use.
Brief Description

DBIBB is a non-lipid agonist of specific lysophosphatidic acid (LPA2) type 2 G-protein-coupled receptor.
Description

DBIBB is a specific nonlipid agonist of the type 2 G protein coupled receptor for lysophosphatidic acid (LPA2). DBIBB mitigates the gastrointestinal radiation syndrome, increases intestinal crypt survival and enterocyte proliferation, and reduces apoptosis. DBIBB represents a agent candidate capable of mitigating acute radiation syndrome caused by high-dose γ-radiation to the hematopoietic and gastrointestinal system.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

LPA Receptor
Recptor

LPA Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

1569309-92-7
Formula Weight

452.48
Molecular Formula

C23H20N2O6S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 100 mg/mL (221.00 mM )
SMILES

OC(=O)c1ccccc1S(=O)(=O)NCCCCN1C(=O)c2cccc3cccc(C1=O)c23
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Patil R, et al. Combined mitigation of the gastrointestinal and hematopoietic acute radiation syndromes by an LPA2 receptor-specific nonlipid agonist. Chem Biol. 2015;22(2):206-216.?

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