D-tetrahydropalmatine

CAS No. 3520-14-7

D-tetrahydropalmatine( —— )

Catalog No. M21452 CAS No. 3520-14-7

D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes and attenuate the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 86 Get Quote
10MG 149 Get Quote
25MG 287 Get Quote
50MG 431 Get Quote
100MG 619 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    D-tetrahydropalmatine
  • Note
    Research use only, not for human use.
  • Brief Description
    D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes and attenuate the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.
  • Description
    D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes and attenuate the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3520-14-7
  • Formula Weight
    355.4
  • Molecular Formula
    C21H25NO4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (140.67 mM)
  • SMILES
    COc(ccc(C1)c2CN(CC3)[C@H]1c(cc1OC)c3cc1OC)c2OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tu M Sun S Wang K et al. Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important role in its hepatotoxicity[J]. Toxicology 2013 311(3):225-230.
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