Cl-C6-PEG4-O-CH2COOH( —— )

Catalog No. M33556 CAS No. 1799506-30-1

Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is an efficient pegylated PROTAC linker commonly used in the synthesis of chloroanes (HaloPROTACs).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	29	Get Quote
10MG	39	Get Quote
25MG	60	Get Quote
50MG	97	Get Quote
100MG	152	Get Quote
500MG	381	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

Cl-C6-PEG4-O-CH2COOH
Note

Research use only, not for human use.
Brief Description

Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is an efficient pegylated PROTAC linker commonly used in the synthesis of chloroanes (HaloPROTACs).
Description

Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs).
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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Chemical Information

CAS Number

1799506-30-1
Formula Weight

370.87
Molecular Formula

C16H31ClO7
Purity

>98% (HPLC)
Solubility

In Vitro:?Ethanol : 100 mg/mL (269.64 mM; Ultrasonic)DMSO : 100 mg/mL (269.64 mM; Ultrasonic )
SMILES

C(OCCOCCOCCCCCCCl)COCCOCC(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Buckley DL, et al.HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10(8):1831-7.?

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