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Cinepazide

CAS No. 23887-46-9

Cinepazide( —— )

Catalog No. M13690 CAS No. 23887-46-9

A cerebral vasodilator that acts as a calcium blocker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Cinepazide
  • Note
    Research use only, not for human use.
  • Brief Description
    A cerebral vasodilator that acts as a calcium blocker.
  • Description
    A cerebral vasodilator that acts as a calcium blocker; protect neuronal cells against OGD injury by suppressing OGD-induced oxidative stress and preserving mitochondrial functions.Ischemia Approved.
  • In Vitro
    ——
  • In Vivo
    Cinepazide (intravenous?injection; 30 mg/kg) potentiates the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, while cinnarizine reduces their vasodilator effects.Cinepazide (intravertebral injection; 1-10 mg/kg) increases vertebral blood flow in a dose-related manner and the effect is partially inhibited by Aminophylline (HY-B0140)?in dogs.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Other Targets
  • Research Area
    Cardiovascular Disease
  • Indication
    Ischemia

Chemical Information

  • CAS Number
    23887-46-9
  • Formula Weight
    417.4986
  • Molecular Formula
    C22H31N3O5
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    COC1=CC(=CC(=C1OC)OC)C=CC(=O)N2CCN(CC2)CC(=O)N3CCCC3
  • Chemical Name
    Piperazine, 1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-, (E)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Miwa S, et al. Jpn J Pharmacol. 1986 May;41(1):109-15. 2. Zhao J, et al. Neurol Sci. 2014 Jun;35(6):875-81. 3. Li Y, et al. Biol Pharm Bull. 2017 Mar 1;40(3):249-255.
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