Cajanin( —— )

Catalog No. M30929 CAS No. 32884-36-9

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Product Name

Cajanin
Note

Research use only, not for human use.
Brief Description

Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol efflux and RCT, it can significantly improve basal glucose uptake in HepG2 cells, its improving effect is concentration dependent, it exhibits effects stronger than that of rosiglitazone, which has been used as an antidiabetic drug.
Description

Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol efflux and RCT, it can significantly improve basal glucose uptake in HepG2 cells, its improving effect is concentration dependent, it exhibits effects stronger than that of rosiglitazone, which has been used as an antidiabetic drug.
In Vitro

Cajanin shows strong mitogenic as well as differentiation-promoting effects on osteoblasts.Cajanin induces the phosphorylation of both Erk1/2 and Akt.
In Vivo

Cajanin (10 mg/kg, p.o.; daily for 30 consecutive days) increases the BMD levelsin all anatomical regions of the skeleton studied in Sprague Dawley rats.
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