CaMKII-IN-1( CaMKII-IN-1 | CaMKII | CaMKII IN-1 | CaMKII IN 1 )

Catalog No. M10773 CAS No. 1208123-85-6

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Product Name

CaMKII-IN-1
Note

Research use only, not for human use.
Brief Description

A potent and highly selective CaMKII inhibitor with IC50 of 63 nM.
Description

A potent and highly selective CaMKII inhibitor with IC50 of 63 nM; no inhibitory effect for CaMKIV, MLCK, p38α, Akt1, PKC etc; shows 25-fold higher potency than KN-93.
In Vitro

——
In Vivo

——
Synonyms

CaMKII-IN-1 | CaMKII | CaMKII IN-1 | CaMKII IN 1
Pathway

Endocrinology/Hormones
Target

CaMK
Recptor

CaMK
Research Area

Inflammation/Immunology
Indication

——

CAS Number

1208123-85-6
Formula Weight

548.0988
Molecular Formula

C29H30ClN5O2S
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 54 mg/mL
SMILES

O=S(C1=CC=CC(Cl)=C1C)(NC2=C(CN(CC3=CC=CC=C3)CC4)C4=NC(NCCC5=CC=CC=C5)=N2)=O
Chemical Name

Benzenesulfonamide, 3-chloro-2-methyl-N-[5,6,7,8-tetrahydro-2-[(2-phenylethyl)amino]-6-(phenylmethyl)pyrido[4,3-d]pyrimidin-4-yl]-

1. Asano S, et al. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6696-8.

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