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CPI-1189

CAS No. 183619-38-7

CPI-1189( CPI-1189 | REN-1189 | REN-1654 | REN1189 )

Catalog No. M17393 CAS No. 183619-38-7

REN-1189 is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 76 In Stock
25MG 155 In Stock
50MG 260 In Stock
100MG 417 In Stock
500MG 888 In Stock
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Biological Information

  • Product Name
    CPI-1189
  • Note
    Research use only, not for human use.
  • Brief Description
    REN-1189 is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
  • Description
    REN-1189 is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
  • In Vitro
    Cell Viability Assay Cell Line:SH-SY5Y oncentration:10, 30, 100, 300 nM Incubation Time:1 h Result:Alleviated OGDR-induced cytotoxicity in a concentration-dependent manner.Apoptosis Analysis Cell Line:SH-SY5Y Concentration:100 nM Incubation Time:1 h Result:Inhibited OGDR-induced caspase-3/-9 activation and ssDNA accumulation.Attenuated OGDR-induced apoptosis activation.
  • In Vivo
    ——
  • Synonyms
    CPI-1189 | REN-1189 | REN-1654 | REN1189
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    TNF-α
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    183619-38-7
  • Formula Weight
    234.3
  • Molecular Formula
    C13H18N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (426.82 mM)
  • SMILES
    CC(=O)Nc1ccc(cc1)C(=O)NC(C)(C)C
  • Chemical Name
    4-acetamido-N-(tert-butyl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bjugstad KB,et al. Preventive actions of a synthetic antioxidant in a novel animal model of AIDS dementia. Brain Res. 1998 Jun 8;795(1-2):349-57.
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