C-171
CAS No. 2244881-69-2
C-171( —— )
Catalog No. M24023 CAS No. 2244881-69-2
C-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 41 | In Stock |
|
| 25MG | 77 | In Stock |
|
| 50MG | 121 | In Stock |
|
| 100MG | 186 | In Stock |
|
| 200MG | 279 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameC-171
-
NoteResearch use only, not for human use.
-
Brief DescriptionC-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
-
DescriptionC-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayImmunology/Inflammation
-
TargetSTING
-
RecptorSTING
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2244881-69-2
-
Formula Weight316.36
-
Molecular FormulaC17H20N2O4
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESO=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(CCCCCC)C=C2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
C-170
C-170 is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research.
-
MSA-2
MSA-2, a potent and orally available non-nucleotide STING agonist, has EC50s of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively. MSA-2 shows antitumor activity and stimulates interferon-β secretion in tumors, induces tumor regression with durable antitumor immunity, and synergizes with anti-PD-1 in syngeneic mouse tumor models.
-
SR-717
SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively.
Cart
sales@molnova.com