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Boc-NH-PEG3
CAS No. 139115-92-7
Boc-NH-PEG3( PROTAC Linker 10 )
Catalog No. M20918 CAS No. 139115-92-7
Boc-NH-PEG3 is a PEG derivative containing a hydroxyl group and Boc-protected amino group and?is a PROTAC linker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 38 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameBoc-NH-PEG3
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NoteResearch use only, not for human use.
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Brief DescriptionBoc-NH-PEG3 is a PEG derivative containing a hydroxyl group and Boc-protected amino group and?is a PROTAC linker.
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DescriptionBoc-NH-PEG3 is a PEG derivative containing a hydroxyl group and Boc-protected amino group and?is a PROTAC linker.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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SynonymsPROTAC Linker 10
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PathwayPROTACs
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TargetPROTAC
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RecptorPROTAC Linker
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Research Area——
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Indication——
Chemical Information
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CAS Number139115-92-7
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Formula Weight249.3
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Molecular FormulaC11H23NO5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (401.12 mM)
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SMILESCC(C)(C)OC(=O)NCCOCCOCCO
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Chemical Nametert-butyl (2-(2-(2-hydroxyethoxy)ethoxy)ethyl)carbamate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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DBCO-S-S-PEG3-biotin
DBCO-S-S-PEG3-biotin is a cleavable reagent for introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry.?The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label.?PEG Linkers can be used in the synthesis of PROTACs.
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Hydroxy-PEG5-Boc
Hydroxy-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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Ac4GalNAz
Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
