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Bisindolylmaleimide X hydrochloride
CAS No. 145317-11-9
Bisindolylmaleimide X hydrochloride( —— )
Catalog No. M32811 CAS No. 145317-11-9
Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective PKC inhibitor and a CDK2 antagonist with an IC50 of 200 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 84 | Get Quote |
|
| 5MG | 123 | Get Quote |
|
| 10MG | 215 | Get Quote |
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| 25MG | 398 | Get Quote |
|
| 50MG | 628 | Get Quote |
|
| 100MG | 853 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBisindolylmaleimide X hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionBisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective PKC inhibitor and a CDK2 antagonist with an IC50 of 200 nM.
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DescriptionBisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective protein kinase C (PKC) inhibitor. Bisindolylmaleimide X hydrochloride is a potent cyclin-dependent kinase 2 (CDK2) antagonist with an IC50 of 200 nM.
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In VitroBisindolylmaleimide X hydrochloride (BIM-X hydrochloride; Ro31-8425 hydrochloride) derivatives acts as an useful tool to compare inhibitor potencies and selectivities for a target of interest.
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetPKC
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RecptorPKC | CDK
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Research Area——
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Indication——
Chemical Information
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CAS Number145317-11-9
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Formula Weight460.96
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Molecular FormulaC26H25ClN4O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 20.83 mg/mL (45.19 mM; Ultrasonic ) H2O : < 0.1 mg/mL (insoluble)
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SMILESCl.Cn1cc(C2=C(C(=O)NC2=O)c2c3CC(CN)CCn3c3ccccc23)c2ccccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Brehmer D, et al. Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors. Mol Cell Proteomics. 2004 May;3(5):490-500.?
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