Bexmarilimab( —— )

Catalog No. M36875 CAS No. 2259301-27-2

Bexmarilimab (FP-1305) is a highly potent, humanized anti-CLEVER-1 IgG4 antibody with an IC50 value of 4.51 nM, promoting immune conversion of tumor-associated macrophage phenotype M2 to M1, and can be used to study cancer.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	301	Get Quote
5MG	820	Get Quote
10MG	1102	Get Quote
25MG	1582	Get Quote
50MG	2144	Get Quote
100MG	2817	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

Bexmarilimab
Note

Research use only, not for human use.
Brief Description

Bexmarilimab (FP-1305) is a highly potent, humanized anti-CLEVER-1 IgG4 antibody with an IC50 value of 4.51 nM, promoting immune conversion of tumor-associated macrophage phenotype M2 to M1, and can be used to study cancer.
Description

Bexmarilimab (FP-1305) is a potent humanized anti-CLEVER-1 IgG4-antibody with an IC50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can be used in research of cancer.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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Chemical Information

CAS Number

2259301-27-2
Formula Weight
Molecular Formula

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Purity

>98% (HPLC)
Solubility

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SMILES

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Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Hollmén M, et, al. Nonclinical Characterization of Bexmarilimab, a Clever-1-Targeting Antibody for Supporting Immune Defense Against Cancers. Mol Cancer Ther. 2022 Jul 5;21(7):1207-1218.?

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