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Beta-d-N4-hydroxycytidine
CAS No. 3258-02-4
Beta-d-N4-hydroxycytidine( NHC )
Catalog No. M14056 CAS No. 3258-02-4
Beta-d-N4-hydroxycytidine (NHC) is a nucleoside analogue that has antipestivirus and antihepacivirus activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 68 | In Stock |
|
| 10MG | 106 | In Stock |
|
| 25MG | 178 | In Stock |
|
| 50MG | 260 | In Stock |
|
| 100MG | 372 | In Stock |
|
| 500MG | 849 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBeta-d-N4-hydroxycytidine
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NoteResearch use only, not for human use.
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Brief DescriptionBeta-d-N4-hydroxycytidine (NHC) is a nucleoside analogue that has antipestivirus and antihepacivirus activities.
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DescriptionBeta-d-N4-hydroxycytidine (NHC) is a nucleoside analogue that has antipestivirus and antihepacivirus activities; inhibits the production of cytopathic BVDV RNA with EC90 of 5.4 uM, also has an EC50 of 5 uM for replicon RNA reduction in Huh7 cells; also is a novel inhibitor of CHIKV (Chikungunya virus), inhibits venezuelan equine encephalitis virus (VEEV) with EC50 of <1 uM.
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In Vitro——
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In Vivo——
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SynonymsNHC
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PathwayMicrobiology/Virology
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TargetHCV
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RecptorHCV
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Research Area——
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Indication——
Chemical Information
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CAS Number3258-02-4
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Formula Weight259.218
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Molecular FormulaC9H13N3O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (385.77 mM)
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SMILESC1=CN(C(=O)N=C1NO)C2C(C(C(O2)CO)O)O
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Chemical Name1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(hydroxyamino)pyrimidin-2(1H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Stuyver LJ, et al. Antimicrob Agents Chemother. 2003 Jan;47(1):244-54.
2. Barnard DL, et al. Antivir Chem Chemother. 2004 Jan;15(1):15-22.
3. Urakova N, et al. J Virol. 2017 Nov 22. pii: JVI.01965-17.
4. Ehteshami M, et al. Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02395-16.
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