Cart
sales@molnova.com
Besifovir
CAS No. 441785-26-8
Besifovir( PMCDG Dipivoxil | ANA-380 | LB-80380 )
Catalog No. M14501 CAS No. 441785-26-8
Besifovir (PMCDG Dipivoxil, NA-380, LB-80380) is a potent, selective, orally available anti-HBV agent, the prodrug of PMCDG (EC50=4 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1143 | Get Quote |
|
| 50MG | 2322 | Get Quote |
|
| 100MG | 3060 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameBesifovir
-
NoteResearch use only, not for human use.
-
Brief DescriptionBesifovir (PMCDG Dipivoxil, NA-380, LB-80380) is a potent, selective, orally available anti-HBV agent, the prodrug of PMCDG (EC50=4 uM).
-
DescriptionBesifovir (PMCDG Dipivoxil, NA-380, LB-80380) is a potent, selective, orally available anti-HBV agent, the prodrug of PMCDG (EC50=4 uM).HBV Infection Phase 3 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsPMCDG Dipivoxil | ANA-380 | LB-80380
-
PathwayMicrobiology/Virology
-
TargetHBV
-
RecptorHBV
-
Research AreaInfection
-
IndicationHBV Infection
Chemical Information
-
CAS Number441785-26-8
-
Formula Weight527.515
-
Molecular FormulaC22H34N5O8P
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCC(C)(C)C(=O)OCOP(=O)(COC1(CC1)CN2C=NC3=CN=C(N=C32)N)OCOC(=O)C(C)(C)C
-
Chemical Name[[1-[(2-aminopurin-9-yl)methyl]cyclopropyl]oxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Choi JR, et al. J Med Chem. 2004 May 20;47(11):2864-9.
2. Yuen MF, et al. Hepatology. 2010 Mar;51(3):767-76.
3. Papatheodoridis GV, et al. Curr Opin Mol Ther. 2006 Aug;8(4):352-7.
molnova catalog
related products
-
GLP-26
GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM.
-
Hepatitis B Virus Co...
The hepatitis B virus (HBV) core protein has been found in the nucleus, the cytoplasm, or both of HBV-infected hepatocytes. nuclear localization of the HBV core protein is negatively regulated by phosphorylation during the cell cycle.
-
NVR 3-778
NVR 3-778 (NVR3-778, NVR 3778) is a small molecule inhibitor of HBV replication that targets the viral core protein, a first-in-class capsid assembly modulator.
