BRD32048( BRD-32048 | BRD 32048 )

Catalog No. M27757 CAS No. 433694-46-3

BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

BRD32048
Note

Research use only, not for human use.
Brief Description

BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.
Description

BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.
In Vitro

——
In Vivo

——
Synonyms

BRD-32048 | BRD 32048
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

TEAD,YAP1/TAZ
Research Area

——
Indication

——

Chemical Information

CAS Number

433694-46-3
Formula Weight

314.393
Molecular Formula

C16H22N6O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (397.60 mM)
SMILES

COc1ccc(cc1)\N=c1/nc(CN2CCCCC2)nc(N)[nH]1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Ayumi Kaneda, et al. The novel potent TEAD inhibitor, K-975, inhibits YAP1/TAZ-TEAD protein-protein interactions and exerts an anti-tumor effect on malignant pleural mesothelioma. Am J Cancer Res. 2020 Dec 1;10(12):4399-4415.

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