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BMS-684
CAS No. 313552-29-3
BMS-684( —— )
Catalog No. M37108 CAS No. 313552-29-3
BMS-684 is a selective and potent DGKα inhibitor (IC50: 15 nM) with potential antitumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 219 | In Stock |
|
| 10MG | 352 | In Stock |
|
| 25MG | 562 | In Stock |
|
| 50MG | 736 | In Stock |
|
| 100MG | 995 | In Stock |
|
| 200MG | 1321 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBMS-684
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NoteResearch use only, not for human use.
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Brief DescriptionBMS-684 is a selective and potent DGKα inhibitor (IC50: 15 nM) with potential antitumor activity.
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DescriptionBMS-684 is a selective DGKα inhibitor with an IC50 of 15 nM. BMS-684 inhibits DGKα kinase activity with >100-fold selectivity over the related DGK type I family members DGKβ and DGKγ. BMS-684 does not inhibit any of the other seven DGK isozymes.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number313552-29-3
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Formula Weight454.52
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Molecular FormulaC27H26N4O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1C([N+]([O-])=O)=C(N2CCN(C(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C5=C(N1C)C=CC=C5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Michael Wichroski, et al. DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity. Sci Transl Med. 2023 Oct 25;15(719):eadh1892. ?
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