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BI-6C9

CAS No. 791835-21-7

BI-6C9( —— )

Catalog No. M20490 CAS No. 791835-21-7

BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission and protected the cells from cell death.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BI-6C9
  • Note
    Research use only, not for human use.
  • Brief Description
    BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission and protected the cells from cell death.
  • Description
    BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission and protected the cells from cell death.
  • In Vitro
    Cell Viability Assay Cell Line:HT-22 cells Concentration:10 μM Incubation Time:18 hours Result:Attenuated Glutamate-induced cell death.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    tBid
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    791835-21-7
  • Formula Weight
    471.59
  • Molecular Formula
    C23H25N3O4S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (530.12 mM)
  • SMILES
    COc1ccc(cc1)S(=O)(=O)NCCCC(=O)Nc1ccc(Sc2ccc(N)cc2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Grohm J Plesnila N Culmsee C . Bid mediates fission membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death[J]. Brain Behavior and Immunity 2010 24(5):0-838.
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