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BAY-3827
CAS No. ——
BAY-3827( BAY3827 )
Catalog No. M17017 CAS No. ——
BAY-3827 (BAY3827) is a potent, selective inhibitor of AMPK .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameBAY-3827
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NoteResearch use only, not for human use.
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Brief DescriptionBAY-3827 (BAY3827) is a potent, selective inhibitor of AMPK .
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DescriptionBAY-3827 (BAY3827) is a potent, selective inhibitor of AMPK as tool compound to evaluate the therapeutic potential of AMPK inhibition in MYC-dependent tumors; strongly inhibits Acetyl-CoA carboxylase (ACC) phosphorylation in COLO 320DM and IMR-32 cells, but fails to inhibit the proliferation of cells with dysregulated c-MYC or N-MYC.
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In Vitro——
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In Vivo——
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SynonymsBAY3827
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PathwayMembrane Transporter/Ion Channel
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TargetAMPK
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RecptorAMPK
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight468.536
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Molecular FormulaC27H25FN6O
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameN-(5-(3,5-dicyano-1,2,6-trimethyl-1,4-dihydropyridin-4-yl)-6-fluoro-7-methyl-1H-indazol-3-yl)-2-ethylbenzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Clara Lemos, et al. Abstract 5873: BAY-3827, a selective inhibitor of AMPK for the evaluation of the role of AMPK in Myc-dependent tumors. AACR.2018.
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