B355252( —— )

Catalog No. M23435 CAS No. 1261576-81-1

B355252 protects against cell death caused by glutamate-evoked oxidative stress.

Purity : >98% (HPLC)

COA

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HNMR

HPLC

MSDS

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10MG	524	In Stock
25MG	840	In Stock
50MG	1143	In Stock
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Biological Information

Product Name

B355252
Note

Research use only, not for human use.
Brief Description

B355252 protects against cell death caused by glutamate-evoked oxidative stress.
Description

B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.
In Vitro

——
In Vivo

B-355252 (0.125 mg/kg; ip; daily; 3 days) significantly attenuates the infarct volume and protects post-stroke neuronal loss in adult male Sprague–Dawley rats with cerebral ischemia.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

1261576-81-1
Formula Weight

514.06
Molecular Formula

C25H24ClN3O3S2
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

C1CN(CCN1)C2=CC(=CC=C2)OC3=C(C=C(S3)S(=O)(=O)NCC4=CC=CC5=CC=CC=C54)Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Chimeh U , Zimmerman M A , Gilyazova N , et al. B355252, A Novel Small Molecule, Confers Neuroprotection Against Cobalt Chloride Toxicity In Mouse Hippocampal Cells Through Altering Mitochondrial Dynamics And Limiting Autophagy Induction[J]. International Journal of Medical Sciences, 2018, 15(12):1384-1396.

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