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Atherosperminine

CAS No. 5531-98-6

Atherosperminine( Atherospermine )

Catalog No. M29285 CAS No. 5531-98-6

Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine exerts a non-specific relaxant effect on the trachealis, its major mechanism of action appears to be inhibition of cAMP phosphodiesterase.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Atherosperminine
Note

Research use only, not for human use.
Brief Description

Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine exerts a non-specific relaxant effect on the trachealis, its major mechanism of action appears to be inhibition of cAMP phosphodiesterase.
Description

Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine exerts a non-specific relaxant effect on the trachealis, its major mechanism of action appears to be inhibition of cAMP phosphodiesterase.(In Vitro):Atherosperminine shows strong anti-plasmodial activity against Plasmodium falciparum, with the IC50 value of 5.80 μM. Atherosperminine also shows antioxidant activity in a DPPH assay with the IC50 value of 54.53 ug/mL.
In Vitro

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In Vivo

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Synonyms

Atherospermine
Pathway

GPCR/G Protein
Target

cAMP
Recptor

cAMP
Research Area

——
Indication

——

Chemical Information

CAS Number

5531-98-6
Formula Weight

309.4
Molecular Formula

C20H23NO2
Purity

>98% (HPLC)
Solubility

——
SMILES

COc1cc(CCN(C)C)c2ccc3ccccc3c2c1OC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

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