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Artemisitene
CAS No. 101020-89-7
Artemisitene( —— )
Catalog No. M23216 CAS No. 101020-89-7
Artemisitene is the oxidized form of Artemisinin and is an antimalarial agent.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 177 | In Stock |
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| 10MG | 312 | In Stock |
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| 25MG | 530 | In Stock |
|
| 50MG | 758 | In Stock |
|
| 100MG | 1044 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameArtemisitene
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NoteResearch use only, not for human use.
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Brief DescriptionArtemisitene is the oxidized form of Artemisinin and is an antimalarial agent.
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DescriptionArtemisitene is the oxidized form of Artemisinin and is an antimalarial agent. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinin B, Artemisitene, Artemisinic acid, etc.
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In VitroArtemisitene selectively induces DNA double-stranded breaks (DSBs) and apoptosis in various human cancer cells by suppressing the expression of topoisomerases in human cancer cells. Artemisitene selectively destabilizes c-Myc in human cancer cells by promoting the ubiquitination of c-Myc through the specific induction of the c-Myc E3 ligase NEDD4.
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In VivoIn Nrf2 wild-type mice, systemic administration of Artemisitene (5-10 mg/kg; i.p.) strongly inhibits bleomycin-induced lung damage.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number101020-89-7
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Formula Weight280.32
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Molecular FormulaC15H20O5
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Purity>98% (HPLC)
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SolubilityDMSO:Soluble
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SMILESC[C@H](CCC1C2=C)[C@H](CC3)[C@]11OO[C@@]3(C)O[C@H]1OC2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Li Y, Wu YL. An over four millennium story behind qinghaosu (artemisinin)--a fantastic antimalarial drug from a traditional chinese herb. Curr Med Chem. 2003 Nov;10(21):2197-230.
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