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Aramchol

CAS No. 246529-22-6

Aramchol( C20-FABAC )

Catalog No. M20671 CAS No. 246529-22-6

Aramchol also known as arachidyl amido cholanoic acid is a conjugate of arachidic acid and cholic acid. It reduces ex vivo cholesterol crystallization in native human bile and dissolves pre-formed cholesterol crystals in a dose-dependent manner.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Aramchol
  • Note
    Research use only, not for human use.
  • Brief Description
    Aramchol also known as arachidyl amido cholanoic acid is a conjugate of arachidic acid and cholic acid. It reduces ex vivo cholesterol crystallization in native human bile and dissolves pre-formed cholesterol crystals in a dose-dependent manner.
  • Description
    Aramchol also known as arachidyl amido cholanoic acid is a conjugate of arachidic acid and cholic acid. It reduces ex vivo cholesterol crystallization in native human bile and dissolves pre-formed cholesterol crystals in a dose-dependent manner.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    C20-FABAC
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Metabolic Disease
  • Indication
    Fibrosis; Non-alcoholic steatohepatitis

Chemical Information

  • CAS Number
    246529-22-6
  • Formula Weight
    702.1
  • Molecular Formula
    C44H79NO5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:53.33 mg/mL (75.96 mM)
  • SMILES
    [H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])[C@H](O)C[C@]2([H])C[C@H](CC[C@]12C)NC(=O)CCCCCCCCCCCCCCCCCCC
  • Chemical Name
    (R)-4-((3S5S7R8R9S10S12S13R14S17R)-712-dihydroxy-3-icosanamido-1013-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Safadi R Konikoff F M Mahamid M et al. The Fatty Acid–Bile Acid Conjugate Aramchol Reduces Liver Fat Content in Patients With Nonalcoholic Fatty Liver Disease[J]. Clinical Gastroenterology and Hepatology 2014 12(12):2085-2091.e1.
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