Anle138b( —— )

Catalog No. M20225 CAS No. 882697-00-9

Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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2MG	30	In Stock
5MG	47	In Stock
10MG	80	In Stock
25MG	174	In Stock
50MG	259	In Stock
100MG	386	In Stock
200MG	556	In Stock
500MG	869	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Anle138b
Note

Research use only, not for human use.
Brief Description

Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease.
Description

Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease.
In Vitro

——
In Vivo

Animal Model:Two‐month‐old PLP‐hαSyn miceDosage:0.6 and 2 g/kg Administration:Oral Result:Prevented motor deficits and neurodegeneration in the PLP‐hαSyn mice.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

others
Research Area

——
Indication

——

Chemical Information

CAS Number

882697-00-9
Formula Weight

343.17
Molecular Formula

C16H11BrN2O2?
Purity

>98% (HPLC)
Solubility

DMSO:50 mg/mL?(145.70 mM)
SMILES

C1OC2=C(O1)C=C(C=C2)C3=CC(=NN3)C4=CC(=CC=C4)Br
Chemical Name

5-(13-Benzodioxol-5-yl)-3-(3-bromophenyl)-1H-pyrazole

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Wagner J et al. Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathol. 2013 Jun;125(6):795-813.

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