Afloqualone( HQ-495 )

Catalog No. M19814 CAS No. 56287-74-2

Afloqualone is a agonist of GABA receptor . Target: GABA Receptor in vitro: Afloqualone is a quinazolinone family GABAergic drug. Afloqualone is an analogue of methaqualone.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Afloqualone
Note

Research use only, not for human use.
Brief Description

Afloqualone is a agonist of GABA receptor . Target: GABA Receptor in vitro: Afloqualone is a quinazolinone family GABAergic drug. Afloqualone is an analogue of methaqualone.
Description

Afloqualone is a agonist of GABA receptor . Target: GABA Receptor in vitro: Afloqualone is a quinazolinone family GABAergic drug. Afloqualone is an analogue of methaqualone. It has sedative and muscle-relaxant effects resulting from its agonist activity at the β subtype of the GABAa receptor.
In Vitro

——
In Vivo

——
Synonyms

HQ-495
Pathway

Others
Target

Other Targets
Recptor

GABAR
Research Area

——
Indication

——

Chemical Information

CAS Number

56287-74-2
Formula Weight

283.3
Molecular Formula

C16H14FN3O
Purity

>98% (HPLC)
Solubility

DMSO:≥33 mg/mL (116.48 mM)
SMILES

Cc1ccccc1-n1c(CF)nc2ccc(N)cc2c1=O
Chemical Name

6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Yamamura M et al. Effects of afloqualone a new centrally acting muscle relaxant on DRL response and CER in rats (author's transl). Nihon Yakurigaku Zasshi. 1981 Oct;78(4):381-92.

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