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AZD8542
CAS No. 1126366-36-6
AZD8542( —— )
Catalog No. M34171 CAS No. 1126366-36-6
AZD8542 is an antagonist of Smoothened (SMO) with potential as an [oncology therapeutic].
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 506 | Get Quote |
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| 5MG | 751 | Get Quote |
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| 10MG | 1064 | Get Quote |
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| 25MG | 1536 | Get Quote |
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| 50MG | 2006 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAZD8542
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NoteResearch use only, not for human use.
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Brief DescriptionAZD8542 is an antagonist of Smoothened (SMO) with potential as an [oncology therapeutic].
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DescriptionAZD8542 is an antagonist of Smoothened (SMO), playing an important role in oncology. AZD8542 is a? Hedgehog (Hh) pathway antagonist on tumor progression with an emphasis on the role of the stroma compartment.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetHedgehog (Hh)
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RecptorHedgehog/Smoothened | Smo
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Research Area——
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Indication——
Chemical Information
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CAS Number1126366-36-6
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Formula Weight412.48
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Molecular FormulaC25H24N4O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC1=CC(C=2N=CN(C2)C)=C(C=C1C)C)C3=CC=C(OCC4=NC=CC=C4)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Rosa F. Hwang, INHIBITION OF THE HEDGEHOG PATHWAY TARGETS THE TUMOR-ASSOCIATED STROMA IN PANCREATIC CANCER. Mol Cancer Res. 2012 Sep; 10(9): 1147–1157.
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