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AVE5688
CAS No. 613260-13-2
AVE5688( —— )
Catalog No. M32794 CAS No. 613260-13-2
AVE5688, an inhibitor of glycogen phosphorylase (GP), has IC50 values of 430 nM and 915 nM, and Kd values of 170 nM and 530 nM for rmGPb and rmGPa, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 429 | Get Quote |
|
| 5MG | 426 | Get Quote |
|
| 10MG | 599 | Get Quote |
|
| 25MG | 861 | Get Quote |
|
| 50MG | 1141 | Get Quote |
|
| 100MG | 1521 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAVE5688
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NoteResearch use only, not for human use.
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Brief DescriptionAVE5688, an inhibitor of glycogen phosphorylase (GP), has IC50 values of 430 nM and 915 nM, and Kd values of 170 nM and 530 nM for rmGPb and rmGPa, respectively.
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DescriptionAVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes.
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In VitroAVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively).
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorPhosphorylase
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Research Area——
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Indication——
Chemical Information
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CAS Number613260-13-2
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Formula Weight438.69
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Molecular FormulaC16H8ClF5N2O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (227.95 mM; Ultrasonic )
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SMILESO(C(F)(F)F)C1=C(NC(NC(=O)C2=C(Cl)C=C(F)C(F)=C2)=O)C=CC(C(O)=O)=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Anderka O, et al. Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors. Biochemistry. 2008 Apr 22;47(16):4683-91.?
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