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AN3199
CAS No. 1187187-10-5
AN3199( —— )
Catalog No. M32778 CAS No. 1187187-10-5
AN3199 is a selective inhibitor of PDE4 with an IC50 of 94.5 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 34 | Get Quote |
|
| 10MG | 55 | Get Quote |
|
| 25MG | 109 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAN3199
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NoteResearch use only, not for human use.
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Brief DescriptionAN3199 is a selective inhibitor of PDE4 with an IC50 of 94.5 nM.
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DescriptionAN3199 is a PDE4 inhibitor with an IC50 of 94.5 nM. AN3199 can be used for the research of inflammation-associated diseases such as asthma and chronic obstructive pulmonary disease (COPD).
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In VitroAN3199 (compound 11) (1 h) disappears (98.0%) is mainly converts to corresponding acid (76.6) in mouse plasma.
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetPDE
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RecptorPDE
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Research Area——
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Indication——
Chemical Information
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CAS Number1187187-10-5
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Formula Weight327.14
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Molecular FormulaC17H18BNO5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (305.68 mM; Ultrasonic )
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SMILESCCCCOC(=O)c1ccc(Oc2ccc3B(O)OCc3c2)nc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhang YK, et al. Design and synthesis of boron-containing PDE4 inhibitors using soft-drug strategy for potential dermatologic anti-inflammatory application. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2270-4.?
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