AG-13958

CAS No. 319460-94-1

AG-13958( AG-013958 )

Catalog No. M20778 CAS No. 319460-94-1

AG-13958 (AG-013958) a potent VEGFR tyrosine kinase inhibitor ?for the treatment of age-related macular degeneration.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 162 In Stock
5MG 314 In Stock
10MG 470 In Stock
25MG 762 In Stock
50MG 1053 In Stock
100MG 1422 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AG-13958
  • Note
    Research use only, not for human use.
  • Brief Description
    AG-13958 (AG-013958) a potent VEGFR tyrosine kinase inhibitor ?for the treatment of age-related macular degeneration.
  • Description
    AG-13958 (AG-013958) a potent VEGFR tyrosine kinase inhibitor ?for the treatment of age-related macular degeneration.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AG-013958
  • Pathway
    Angiogenesis
  • Target
    VEGFR
  • Recptor
    VEGFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    319460-94-1
  • Formula Weight
    467.5
  • Molecular Formula
    C26H22FN7O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:5 mg/mL (10.70 mM)
  • SMILES
    Cc1cc(C(=O)Nc2cc(Nc3ccc4c(/C=C/c5ccccn5)n[nH]c4c3)ccc2F)n(C)n1
  • Chemical Name
    N-[2-Fluoro-5-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]amino]phenyl]-13-dimethyl-1H-pyrazole-5-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Barakat M R Kaiser P . VEGF inhibitors for the treatment of neovascular age-related macular degeneration[J]. Expert Opinion on Investigational Drugs 2009 18(5):637-646.
molnova catalog
related products
  • Telatinib

    An orally active, small molecule inhibitor of VEGFR-2 (IC50=6 nM), VEGFR-3 (IC50=4 nM), PDEGFRα (IC50=15 nM) and c-Kit (IC50=1 nM) in biochemical assays.

  • CL-387785

    CL-387785(EKI785; WAY-EKI 785) is an irreversible inhibitor of EGFR(IC50: 370+/-120 pM);is able to overcome resistance caused by the T790M mutation on a functional level.

  • Veratric acid

    Veratric acid plays an important role in producing antibiotics and various dyes.