6-Azido-hexylamine

Research use only, not for human use.

6-Azido-hexylamine is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs).

6-Azido-hexylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 6-Azido-hexylamine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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Antibody Drug Conjugates (ADC)

ADCs Linker/Click Chemistry

ADC Linker

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349553-73-7

142.2022

C6H14N4

>98% (HPLC)

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NCCCCCCN=[N+]=[N-]

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(-20℃)

With Ice Pack

≥ 2 years