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4-Methylpyrazole
CAS No. 7554-65-6
4-Methylpyrazole( 4-Methylpyrazole )
Catalog No. M15874 CAS No. 7554-65-6
Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 28 | In Stock |
|
| 500MG | 43 | In Stock |
|
| 1G | 45 | In Stock |
|
Biological Information
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Product Name4-Methylpyrazole
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NoteResearch use only, not for human use.
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Brief DescriptionFomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.
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DescriptionFomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites. (In Vivo):Pretreatment with Fomepizole (4-Methylpyrazole; 25 mg/kg; IP) prolongs ethanol neurobehavioral toxicity in CD-1 mice.
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In Vitro——
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In VivoPretreatment with Fomepizole (4-Methylpyrazole; 25 mg/kg; IP) prolongs ethanol neurobehavioral toxicity in CD-1 mice Animal Model:Male CD-1 mice weighing 18-25 gDosage:25 mg/kg Administration:IP; single dose Result:Decreased the dose of ethanol (1-5 g/kg; IP) at which 50% of the animals failed a particular outcome test (toxic dose 50; TD50).
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Synonyms4-Methylpyrazole
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptorADH| CAT
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number7554-65-6
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Formula Weight82.1
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Molecular FormulaC4H6N2
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Purity>98% (HPLC)
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SolubilityWater: 146 mg/mL
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SMILESCC1=CNN=C1
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Chemical Name4-methyl-1H-pyrazole
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Nagata H, et al. Am J Physiol. 1996 Dec;271(6 Pt 1):G1028-33.
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