Cart
sales@molnova.com
21-deacetyldeflazacort
CAS No. 13649-57-5
21-deacetyldeflazacort( —— )
Catalog No. M27940 CAS No. 13649-57-5
21-deacetyldeflazacort is a metabolite of Deflazacort, which is a systemic corticosteroid and a derivative of prednisolone.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 149 | Get Quote |
|
| 10MG | 221 | Get Quote |
|
| 25MG | 374 | Get Quote |
|
| 50MG | 534 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product Name21-deacetyldeflazacort
-
NoteResearch use only, not for human use.
-
Brief Description21-deacetyldeflazacort is a metabolite of Deflazacort, which is a systemic corticosteroid and a derivative of prednisolone.
-
Description21-deacetyldeflazacort is a metabolite of Deflazacort, which is a systemic corticosteroid and a derivative of prednisolone.(In Vitro):21-deacetyldeflazacort displaces [3H]dexamethasone from its cytosol receptor sites in rat kidney, thymus and liver in vitro.(In Vivo):21-deacetyldeflazacort inhibited 48-h homologous passive cutaneous anaphylaxis in rats, but had no significant effects on active systemic anaphylaxis in mice, on the Schultz-Dale reaction in the isolated guinea-pig trachea or on compound 48/80-induced histamine release in rat peritoneal mast cells. 21-deacetyldeflazacort inhibited reversed cutaneous anaphylaxis in rats and the Arthus reaction in mice.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number13649-57-5
-
Formula Weight399.487
-
Molecular FormulaC23H29NO5
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (625.81 mM)
-
SMILESCC1=N[C@@]2([C@@H](C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]23C)O1)C(=O)CO
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Thielen LA, et al. Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action. Cell Metab. 2020 Sep 1;32(3):353-365.e8.
molnova catalog
related products
-
2-Methoxyethanol
2-Methoxyethanol is used in the synthesis of 2-aminothiazoles in the treatment of prion disease. 2-Methoxyethanol is also used in the preparation of Rho-associated kinase inhibitors or (ROCK) inhibitors for the treatment of cardiovascular disease.
-
Oleuropein
Oleuropein is an antioxidant polyphenol isolated from olive leaf.
-
Riluzole hydrochlori...
Riluzole hydrochloride (PK 26124 hydrochloride) is an anticonvulsant compound belonging to the family of sodium channel blockers that inhibits GABA uptake.
