2-C-Methyladenosine

CAS No. 15397-12-3

2-C-Methyladenosine( —— )

Catalog No. M35432 CAS No. 15397-12-3

2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication and a ribonucleoside diphosphate reductase inhibitor from Corynebacterium renalis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 29 In Stock
10MG 43 In Stock
25MG 82 In Stock
50MG 135 In Stock
100MG 205 In Stock
500MG 516 In Stock
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Biological Information

  • Product Name
    2-C-Methyladenosine
  • Note
    Research use only, not for human use.
  • Brief Description
    2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication and a ribonucleoside diphosphate reductase inhibitor from Corynebacterium renalis.
  • Description
    2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication. 2'-C-Methyladenosine inhibits HCV replicon and NS5B-catalyzed RNA synthesis with IC50 values of 0.3μM and 1.9 μM, respectively. 2'-C-Methyladenosine also potently inhibits LRV1 in Leishmania guyanensis (Lgy) and Leishmania braziliensis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    HCV Protease
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    15397-12-3
  • Formula Weight
    281.27
  • Molecular Formula
    C11H15N5O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 31.25 mg/mL (111.10 mM; Ultrasonic (<60°C)
  • SMILES
    C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Steven S Carroll, et al. Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs. J Biol Chem. 2003 Apr 4;278(14):11979-84.?
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