(±)8(9)-EpETE

Research use only, not for human use.

Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE.

Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE , relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo. The biological actions and physiological effects of this epoxide remain to be determined.

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Others

Other Targets

Others

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851378-93-3

318.457

C20H30O3

>98% (HPLC)

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CC\C=C/C\C=C/C\C=C/CC1OC1C\C=C/CCCC(O)=O

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(-20℃)

With Ice Pack

≥ 2 years