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(Z)-Thiothixene

CAS No. 3313-26-6

(Z)-Thiothixene( Thiothixene | cis-Thiothixene | Navane )

Catalog No. M26530 CAS No. 3313-26-6

(Z)-Thiothixene is an serotonergic receptor antagonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (Z)-Thiothixene
  • Note
    Research use only, not for human use.
  • Brief Description
    (Z)-Thiothixene is an serotonergic receptor antagonist.
  • Description
    (Z)-Thiothixene is an serotonergic receptor antagonist.(In Vitro):(Z)-Thiothixene promotes cell survival and plasticity. (Z)-Thiothixene inhibits cell death, especially when toxic substances are exposed to cells including neuronal cells .
  • In Vitro
    (Z)-Thiothixene is capable of promoting cell survival and/or plasticity, and/or inhibiting cell death, especially when a toxic agent is exposed to the cells, including neuronal cells. (Z)-Thiothixene is a Z (cis) isomer of thiothixene, as well as synthetic precursor and degradant.
  • In Vivo
    ——
  • Synonyms
    Thiothixene | cis-Thiothixene | Navane
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    5-HT2A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3313-26-6
  • Formula Weight
    443.62
  • Molecular Formula
    C23H29N3O2S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 10 mg/mL (22.54 mM)
  • SMILES
    CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN3CCN(C)CC3)c2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Vanover KE, Harvey SC, Son T, Bradley SR, Kold H, Makhay M, Veinbergs I, Spalding TA, Weiner DM, Andersson CM, Tolf BR, Brann MR, Hacksell U, Davis RE. Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist. J Pharmacol Exp Ther. 2004 Sep;310(3):943-51. Epub 2004 Apr 21.
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