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(Z)-PUGNAc
CAS No. 132489-69-1
(Z)-PUGNAc( —— )
Catalog No. M35061 CAS No. 132489-69-1
(Z)-PUGNAc, a potent O-GlcNAcase inhibitor more active than (E)-PUGNAc, removes O-GlcNAc from proteins (peptide O-GlcNAc-β-N-acetylaminoglucosidase) and can be used to increase levels of O-GlcNAc on nuclear and cytoplasmic proteins in vivo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 100 | In Stock |
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| 5MG | 150 | In Stock |
|
| 10MG | 278 | In Stock |
|
| 25MG | 457 | In Stock |
|
| 50MG | 668 | In Stock |
|
| 100MG | 882 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(Z)-PUGNAc
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NoteResearch use only, not for human use.
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Brief Description(Z)-PUGNAc, a potent O-GlcNAcase inhibitor more active than (E)-PUGNAc, removes O-GlcNAc from proteins (peptide O-GlcNAc-β-N-acetylaminoglucosidase) and can be used to increase levels of O-GlcNAc on nuclear and cytoplasmic proteins in vivo.
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Description(Z)-PUGNAc is a potent O-GlcNAcase inhibitor. (Z)-PUGNAc is a vastly more potent inhibitor of O-GlcNAcase than the E form.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number132489-69-1
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Formula Weight353.33
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Molecular FormulaC15H19N3O7
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (141.51 mM; Ultrasonic )
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SMILESCC(=O)NC1C(O)C(O)C(CO)OC1=NOC(=O)Nc1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Perreira M, et al. Inhibition of O-GlcNAcase by PUGNAc is dependent upon the oxime stereochemistry. Bioorg Med Chem. 2006;14(3):837-846. ?
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