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Home - Products - Antibody Drug Conjugates (ADC) - ADC Cytotoxin - (4-NH2)-Exatecan

(4-NH2)-Exatecan

CAS No. 2495742-21-5

(4-NH2)-Exatecan( —— )

Catalog No. M35185 CAS No. 2495742-21-5

(4-NH2)-Exatecan is a topoisomerase inhibitor with potential anticancer activity for the synthesis of antibody drug conjugates (ADCs).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (4-NH2)-Exatecan
  • Note
    Research use only, not for human use.
  • Brief Description
    (4-NH2)-Exatecan is a topoisomerase inhibitor with potential anticancer activity for the synthesis of antibody drug conjugates (ADCs).
  • Description
    (4-NH2)-Exatecan, a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs) (US20200306243A1, compound A).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADC Cytotoxin
  • Recptor
    ADC Cytotoxin | Topoisomerase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2495742-21-5
  • Formula Weight
    403.43
  • Molecular Formula
    C23H21N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (247.87 mM; Ultrasonic )
  • SMILES
    CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(N)c5CCCc(c3Cn1c2=O)c45
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Howard PW, et, al. Compounds and conjugates thereof. US20200306243A1.
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