SMO-IN-2
SMO-IN-2
Catalog No. M35720
SMO-IN-2 is a potent smoothened (SMO) inhibitor of hedgehog (Hh) signaling.SMO-IN-2 shows antiproliferative activity and anticancer activity against human medulloblastoma cell lines.SMO-IN-2 can be used in the study of cancer.
| Size | Price / USD | Stock | Quantity |
| 5MG | 252 | In Stock |
|
| 10MG | 378 | In Stock |
|
| 25MG | 618 | In Stock |
|
| 50MG | 814 | In Stock |
|
| 100MG | 1088 | In Stock |
|
| 200MG | 1469 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSMO-IN-2
-
Brief Description
-
Description
-
Storage
-
NoteResearch use only, not for human use.
-
Reference1. Ji D, et al. Design, synthesis and biological evaluation of anthranilamide derivatives as potent SMO inhibitors. Bioorg Med Chem. 2020 Mar 15;28(6):115354.?
molnova catalog
related products
-
Cucurbitacin B
Cucurbitacin B has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN.
-
Robotnikinin
Robotnikinin is asmall molecule that binds the extracellular Sonic Hedgehog (Shh) protein (Kd=3.1 uM) and blocks Shh-signaling in cell lines.
-
Purmorphamine
Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM in HEK293T cell and also is an inducer of osteoblast differentiation with EC50 of 1 μM.
Cart
sales@molnova.com