Lyn peptide inhibitor

Lyn peptide inhibitor

Catalog No. M30653

Cell-permeable inhibitor of Lyn-dependent effects of the IL-5 receptor. Blocks binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors, blocking Lyn activation. Inhibits IL-5 receptor-mediated eosinophil differentiation and survival in vitro. Inhibits airway eosinophilic inflammation in mouse model of asthma.

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Biological Information

  • Product Name
    Lyn peptide inhibitor
  • Brief Description
  • Description
  • Storage
  • Note
    Research use only, not for human use.
  • Reference
    1. Adachi et al (1999) The mapping of the Lyn kinase binding site of the common β subunit of IL-3/granulocyte-macrophage colony-stimulating factor/IL-5 receptor. J.Immunol. 162 1496 PMID:
molnova catalog
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